Windows 2008 Server Backup - fatal error - cannot find path specified

I have added the Windows Server Backup feature to a couple of our Server 2008 Standard edition servers.  When I launch it, I get a message:
A fatal error occurred during a windows Server Backup snap-in operation.
The system cannot find the path specified.
Close windows server Backup and then restart it.

Restarting doesn't help, nor does a restart of the server itself.  I'm getting the same error on both servers, one a Dell PowerEdge 1900 and the other a PowerEdge 2950 III. 

What is the path that it is looking for?

Thanks for any assistance!
Charles